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Straight Lab

A Biochemistry Sub-site Tagline (if needed)

  • Dr. Paul Straight’s Lab
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Publications

  1. LaBonte, S, Liu, Y, Powers, M, De Ford, E, Straight, PD. Chloramphenicol-mobilized Bacillus subtilis transiently expresses resistance to multiple antibiotics, including the glycopeptides phleomycin and bleomycin. bioRxiv. 2025; :. doi: 10.1101/2025.01.13.632840. PubMed PMID:39868268 PubMed Central PMC11761127.
  2. Straight, PJ, Gignac, PM, Kuenzel, WJ. A histological and diceCT-derived 3D reconstruction of the avian visual thalamofugal pathway. Sci Rep. 2024;14 (1):8447. doi: 10.1038/s41598-024-58788-z. PubMed PMID:38600121 PubMed Central PMC11006926.
  3. Liu, Y, LaBonte, S, Brake, C, LaFayette, C, Rosebrock, AP, Caudy, AA et al.. MOB rules: Antibiotic Exposure Reprograms Metabolism to Mobilize Bacillus subtilis in Competitive Interactions. bioRxiv. 2024; :. doi: 10.1101/2024.03.20.585991. PubMed PMID:38562742 PubMed Central PMC10983992.
  4. Fernández, A, Classen, A, Josyula, N, Florence, JT, Sokolov, AV, Scully, MO et al.. Simultaneous Two- and Three-Photon Deep Imaging of Autofluorescence in Bacterial Communities. Sensors (Basel). 2024;24 (2):. doi: 10.3390/s24020667. PubMed PMID:38276359 PubMed Central PMC10819415.
  5. Straight, PJ, Gignac, PM, Kuenzel, WJ. Mapping the avian visual tectofugal pathway using 3D reconstruction. J Comp Neurol. 2024;532 (2):e25558. doi: 10.1002/cne.25558. PubMed PMID:38047431 .
  6. Zhang, C, Straight, PD. Antibiotic discovery through microbial interactions. Curr Opin Microbiol. 2019;51 :64-71. doi: 10.1016/j.mib.2019.06.006. PubMed PMID:31344518 .
  7. Liu, Y, Kyle, S, Straight, PD. Antibiotic Stimulation of a Bacillus subtilis Migratory Response. mSphere. 2018;3 (1):. doi: 10.1128/mSphere.00586-17. PubMed PMID:29507890 PubMed Central PMC5821984.
  8. Stubbendieck, RM, Brock, DJ, Pellois, JP, Gill, JJ, Straight, PD. Linearmycins are lytic membrane-targeting antibiotics. J Antibiot (Tokyo). 2018;71 (3):372-381. doi: 10.1038/s41429-017-0005-z. PubMed PMID:29348524 .
  9. Hoefler, BC, Stubbendieck, RM, Josyula, NK, Moisan, SM, Schulze, EM, Straight, PD et al.. A Link between Linearmycin Biosynthesis and Extracellular Vesicle Genesis Connects Specialized Metabolism and Bacterial Membrane Physiology. Cell Chem Biol. 2017;24 (10):1238-1249.e7. doi: 10.1016/j.chembiol.2017.08.008. PubMed PMID:28919037 .
  10. Stubbendieck, RM, Straight, PD. Linearmycins Activate a Two-Component Signaling System Involved in Bacterial Competition and Biofilm Morphology. J Bacteriol. 2017;199 (18):. doi: 10.1128/JB.00186-17. PubMed PMID:28461449 PubMed Central PMC5573067.
  11. Goodson, JR, Klupt, S, Zhang, C, Straight, P, Winkler, WC. LoaP is a broadly conserved antiterminator protein that regulates antibiotic gene clusters in Bacillus amyloliquefaciens. Nat Microbiol. 2017;2 :17003. doi: 10.1038/nmicrobiol.2017.3. PubMed PMID:28191883 PubMed Central PMC5913657.
  12. Stubbendieck, RM, Vargas-Bautista, C, Straight, PD. Bacterial Communities: Interactions to Scale. Front Microbiol. 2016;7 :1234. doi: 10.3389/fmicb.2016.01234. PubMed PMID:27551280 PubMed Central PMC4976088.
  13. Stubbendieck, RM, Straight, PD. Multifaceted Interfaces of Bacterial Competition. J Bacteriol. 2016;198 (16):2145-55. doi: 10.1128/JB.00275-16. PubMed PMID:27246570 PubMed Central PMC4966439.
  14. Stubbendieck, RM, Straight, PD. Correction: Escape from Lethal Bacterial Competition through Coupled Activation of Antibiotic Resistance and a Mobilized Subpopulation. PLoS Genet. 2016;12 (1):e1005807. doi: 10.1371/journal.pgen.1005807. PubMed PMID:26752286 PubMed Central PMC4709098.
  15. Stubbendieck, RM, Straight, PD. Escape from Lethal Bacterial Competition through Coupled Activation of Antibiotic Resistance and a Mobilized Subpopulation. PLoS Genet. 2015;11 (12):e1005722. doi: 10.1371/journal.pgen.1005722. PubMed PMID:26647299 PubMed Central PMC4672918.
  16. Müller, S, Strack, SN, Hoefler, BC, Straight, PD, Kearns, DB, Kirby, JR et al.. Bacillaene and sporulation protect Bacillus subtilis from predation by Myxococcus xanthus. Appl Environ Microbiol. 2014;80 (18):5603-10. doi: 10.1128/AEM.01621-14. PubMed PMID:25002419 PubMed Central PMC4178607.
  17. Vargas-Bautista, C, Rahlwes, K, Straight, P. Bacterial competition reveals differential regulation of the pks genes by Bacillus subtilis. J Bacteriol. 2014;196 (4):717-28. doi: 10.1128/JB.01022-13. PubMed PMID:24187085 PubMed Central PMC3911183.
  18. Hoefler, BC, Konganti, K, Straight, PD. De Novo Assembly of the Streptomyces sp. Strain Mg1 Genome Using PacBio Single-Molecule Sequencing. Genome Announc. 2013;1 (4):. doi: 10.1128/genomeA.00535-13. PubMed PMID:23908282 PubMed Central PMC3731836.
  19. Meyer, RE, Kim, S, Obeso, D, Straight, PD, Winey, M, Dawson, DS et al.. Mps1 and Ipl1/Aurora B act sequentially to correctly orient chromosomes on the meiotic spindle of budding yeast. Science. 2013;339 (6123):1071-4. doi: 10.1126/science.1232518. PubMed PMID:23371552 PubMed Central PMC3604795.
  20. Hoefler, BC, Gorzelnik, KV, Yang, JY, Hendricks, N, Dorrestein, PC, Straight, PD et al.. Enzymatic resistance to the lipopeptide surfactin as identified through imaging mass spectrometry of bacterial competition. Proc Natl Acad Sci U S A. 2012;109 (32):13082-7. doi: 10.1073/pnas.1205586109. PubMed PMID:22826229 PubMed Central PMC3420176.
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Recent Publications

  1. LaBonte, S, Liu, Y, Powers, M, De Ford, E, Straight, PD. Chloramphenicol-mobilized Bacillus subtilis transiently expresses resistance to multiple antibiotics, including the glycopeptides phleomycin and bleomycin. bioRxiv. 2025; :. doi: 10.1101/2025.01.13.632840. PubMed PMID:39868268 PubMed Central PMC11761127.
  2. Straight, PJ, Gignac, PM, Kuenzel, WJ. A histological and diceCT-derived 3D reconstruction of the avian visual thalamofugal pathway. Sci Rep. 2024;14 (1):8447. doi: 10.1038/s41598-024-58788-z. PubMed PMID:38600121 PubMed Central PMC11006926.
Search PubMed
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